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Search Results for " adenosine deaminase "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T19179	Adenosine deaminase		Others
	Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of 2'-deoxyadenosine and adenosine to 2'-deoxyinosine and inosine, respectively.		Others
T9111	8-Azaadenosine		Adenosine deaminase
	8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells.		Adenosine deaminase
T4006	Pentostatin	Nipent,CI-825,Covidarabine,Deoxycoformycin	Adenosine deaminase , Adenosine Receptor
	Pentostatin (CI-825) is an extremely effective and irreversible inhibitor of adenosine deaminase (Ki: 2.5 pM).		Adenosine deaminase , Adenosine Receptor
T2558	Cladribine	2-chlorodeoxyadenosine,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA	Apoptosis , Adenosine deaminase
	Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.		Apoptosis , Adenosine deaminase
T50029	2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine	2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine	Others
	2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine (2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine) is a heterocyclic compound. It inhibits monoamine oxidase, resulting in elevated monoamine levels in the body. It can...		Others
TNU0060	3’-O-Methyladenosine		Antiviral , Adenosine deaminase
	3’-O-Methyladenosine is an antiviral compound with inhibitory activity against West Nile Virus and can be used for the treatment of viral infections.3’-O-Methyladenosine inhibits adenosine deaminase type VII with a Ki va...		Antiviral , Adenosine deaminase
T23634	Adecypenol	OM-3223,OM3223,OM 3223,Antibiotic OM 3223
	Adecypenol is a unique adenosine deaminase inhibitor. It shows effective inhibitory activity against calf intestinal adenosine deaminase.
T27384	FR-234938	FR 234938
	FR-234938 is a non-nucleoside adenosine deaminase inhibitor with anti-inflammatory activity.
T70255	Elapegademase
	Elapegademase is an Adenosine Deaminase Inhibitor
T27383	FR-221647
	FR-221647 is a non-nucleoside adenosine deaminase inhibitor, it has moderate activity and good pharmacokinetics compared with the known inhibitors EHNA and pentostatin.
T10015	1-Deazaadenosine		Others
	1-Deazaadenosine is a potent Adenosine deaminase inhibitor (Ki: 0.66 μM). It exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders.		Others
T10308	AMPD2 inhibitor 1		Others
	AMPD2 inhibitor 1 is an inhibitor of adenosine monophosphate deaminase 2 (AMPD2), used in the research of salt craving, sugar craving, umami craving, and addictions including tobacco, drug, nicotine and alcohol addiction...		Others
T37106	2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)
	2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibi...
T38346	ABT 702 hydrochloride
	Potent non-nucleoside adenosine kinase inhibitor (IC50 = 1.7 nM), selective over other sites of adenosine interaction (A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase). Displays oral activity in a...
T40566	2′-O-(2-Methoxyethyl)guanosine	2′-O-(2-Methoxyethyl)guanosine,2'-O-MOE-rG
	2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a modified nucleoside, can be enzymatically converted from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside by adenosine deaminase. However, this compound is not readily phos...
T60701	Fludarabine-Cl
	Fludarabine-Cl shows inhibition effect on RNA adenosine deaminase 1(ADAR1) that can be used for preventing and/or treating diseases related with cancer or tumor [1].
T11168	EHNA hydrochloride		Others
	EHNA hydrochloride is a chemical compound recognized for its antiviral, antitumor, and antiarrhythmic properties. It functions as a potent and selective inhibitor of both cyclic nucleotide phosphodiesterase 2 (PDE2) with...		Others

Compounds

Adenosine deaminase

Target: Adenosine deaminase

Pentostatin

T4006

Synonym: Nipent,CI-825,Covidarabine,Deoxycoformycin

Target: Adenosine deaminase, Adenosine Receptor

Cladribine

T2558

Synonym: 2-chlorodeoxyadenosine,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA

Target: Apoptosis, Adenosine deaminase

2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine

T50029

Synonym: 2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine

Target: Antiviral, Adenosine deaminase

Adecypenol

T23634

Synonym: OM-3223,OM3223,OM 3223,Antibiotic OM 3223

2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)

T37106

Synonym:

Target:

ABT 702 hydrochloride

T38346

Synonym:

Target:

2′-O-(2-Methoxyethyl)guanosine

T40566

Synonym: 2′-O-(2-Methoxyethyl)guanosine,2'-O-MOE-rG

Cat No.	Product Name	Synonyms	Targets
TN1736	Hibifolin		Adenosine deaminase
	Hibifolin is a flavonol glycoside natural product,is a potential inhibitor of adenosine deaminase (Ki of 49.92 μM). Hibifolin protects neurons against beta-amyloid-induced neurotoxicity.		Adenosine deaminase
T13482	2'-O-Methyladenosine		Endogenous Metabolite
	2'-O-Methyladenosine, a methylated adenine residue is found in the urine of normals and adenosine deaminase deficient patients. It shows unique hypotensive activities.		Endogenous Metabolite
T0665	Xanthine	2,6-Dihydroxypurine,Isoxanthine	Endogenous Metabolite , Adenosine Receptor
	Xanthine (Isoxanthine) is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Xanthine is found in most body tissues and fluids in...		Endogenous Metabolite , Adenosine Receptor
T4901	5'-Guanylic acid disodium salt	Guanosine 5'-monophosphate disodium salt,GMP-5	Others , Endogenous Metabolite
	5'-Guanylic acid disodium salt (GMP-5) belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthy...		Others , Endogenous Metabolite
T23905	Coformycin	NSC 277817
	Coformycin is a ribonucleoside antibiotic synergist and adenosine deaminase inhibitor.
T19346	5'-Guanylic acid	5'-guanosine monophosphate,5'-GMP	Endogenous Metabolite
	5'-Guanylic acid (5'-guanosine monophosphate) is involved in several metabolic disorders, including AICA-ribosiduria pathway, adenosine deaminase deficiency,adenine phosphoribosyltransferase deficiency (aprt), and the 2-...		Endogenous Metabolite

Natural Products

Hibifolin

TN1736

Synonym:

Target: Adenosine deaminase

2'-O-Methyladenosine

T13482

Synonym:

Target: Endogenous Metabolite

Xanthine

T0665

Synonym: 2,6-Dihydroxypurine,Isoxanthine

Target: Endogenous Metabolite, Adenosine Receptor

5'-Guanylic acid disodium salt

T4901

Synonym: Guanosine 5'-monophosphate disodium salt,GMP-5

Target: Others, Endogenous Metabolite

Synonym: 5'-guanosine monophosphate,5'-GMP

Target: Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03985	Adenosine Deaminase Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Adenosine Desaminase (ADA) deficiency, is a purine metabolic disorder that cause severe combined immunodeficiency (SCID) due to the accumulation of toxic metabolites that primarily affects development, differentiation a...
TMPY-00516	CECR1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	CECR1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.3 kDa and the accession number is AAH51755.1.
TMPH-01248	ADAR Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
TMPH-01249	ADAR Protein, Human, Recombinant (GST)	Human	E. coli
	ADAR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 47.2 kDa and the accession number is P55265.

Adenosine Deaminase Protein, Human, Recombinant (His)

TMPY-03985

Species: Human

Expression System: Baculovirus Insect Cells

CECR1 Protein, Human, Recombinant (His)

TMPY-00516

Species: Human

Expression System: Baculovirus Insect Cells

ADAR Protein, Human, Recombinant (His & SUMO)

TMPH-01248

Species: Human

Expression System: E. coli

ADAR Protein, Human, Recombinant (GST)

TMPH-01249

Species: Human

Expression System: E. coli